Improving spatiotemporal resolution of USPIO-enhanced dynamic imaging of rat kidneys.
Ying Sun
Dewen Yang
Qing Ye
Mangay Williams
José M. F. Moura
Fernando Boada
Zhi-Pei Liang
Chien Ho
10.1184/R1/6099638.v1
https://kilthub.cmu.edu/articles/journal_contribution/Improving_spatiotemporal_resolution_of_USPIO-enhanced_dynamic_imaging_of_rat_kidneys_/6099638
<p>This paper addresses the problem of enhancing spatiotemporal resolution of ultra-small superparamagnetic iron oxide (USPIO)-enhanced dynamic MRI of rat kidneys. To alleviate the limited resolution problem of conventional full-scan Fourier imaging methods, we use a generalized series-based imaging scheme to reduce coverage of kappa-space. Experimental results demonstrate that the generalized series imaging method with basis functions constructed using two references (pre- and post-contrast) can reduce the number of phase encodings measured during the dynamic contrast wash-in process by a factor of 4 with a negligible or minimal loss of image quality. The method is expected to make 3D studies possible using USPIO-enhanced dynamic imaging of rat kidneys, and prove valuable for early detection of renal rejection after kidney transplantation.</p>
2003-07-01 00:00:00
Animals
Contrast Media
Dextrans
Ferrosoferric Oxide
Graft Rejection
Image Processing
Computer-Assisted
Iron
Kidney
Kidney Transplantation
Magnetic Resonance Imaging
Magnetite Nanoparticles
Oxides
Rats