%0 Generic %A Mahon, Bradford %A Hirad, Adnan %A Bazarian, Jeffrey %A Merchanr-Borna, Kian %A Garcea, Frank %A Heilbronner, Sarah %A Paul, David %A Hintz, Eric %A van Wijngaarden, Edwin %A Schifitto, Giovanni %A Wright, David %A Espinoza, Tamara %D 2019 %T A common neural signature of brain injury in concussion and sub-concussion %U https://kilthub.cmu.edu/articles/dataset/A_common_neural_signature_of_brain_injury_in_concussion_and_sub-concussion/7964984 %R 10.1184/R1/7964984.v1 %2 https://kilthub.cmu.edu/ndownloader/files/14831996 %2 https://kilthub.cmu.edu/ndownloader/files/14831729 %2 https://kilthub.cmu.edu/ndownloader/files/14831738 %2 https://kilthub.cmu.edu/ndownloader/files/14831741 %2 https://kilthub.cmu.edu/ndownloader/files/14831732 %K National Football League %K Concussions %K neuroimaging studies %K MRI %K MRI maps %X Repetitive Sub-Concussive Head Impacts (RSHI) cohort. Participants were 42 male football players on the University of Rochester football team (NCAA division-III), enrolled over the course of 3 seasons (2011, 2012, 2013). Three subjects were lost to follow-up and 1 subject lacked field map correction scans, yielding 38 complete datasets (mean age = 19.8, median = 20). All of the players sustained repetitive head impacts across the season, but only 2 of the 38 sustained clinically defined concussion/mTBI. For all participants in the RSHI cohort, MRI scanning was carried out 2 weeks prior to the start of the season and within 1 week after completion of the season. In order to record the inertial loading sustained by the players’ brains throughout the season of play, each player wore a helmet-mounted accelerometer that measured linear and rotational acceleration throughout all practices and games. %I Carnegie Mellon University