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A common neural signature of brain injury in concussion and sub-concussion

dataset
posted on 2019-04-08, 18:47 authored by Bradford MahonBradford Mahon, Adnan Hirad, Jeffrey Bazarian, Kian Merchanr-Borna, Frank Garcea, Sarah Heilbronner, David Paul, Eric Hintz, Edwin van Wijngaarden, Giovanni Schifitto, David Wright, Tamara Espinoza
Repetitive Sub-Concussive Head Impacts (RSHI) cohort. Participants were 42 male football players on the University of Rochester football team (NCAA division-III), enrolled over the course of 3 seasons (2011, 2012, 2013). Three subjects were lost to follow-up and 1 subject lacked field map correction scans, yielding 38 complete datasets (mean age = 19.8, median = 20). All of the players sustained repetitive head impacts across the season, but only 2 of the 38 sustained clinically defined concussion/mTBI. For all participants in the RSHI cohort, MRI scanning was carried out 2 weeks prior to the start of the season and within 1 week after completion of the season. In order to record the inertial loading sustained by the players’ brains throughout the season of play, each player wore a helmet-mounted accelerometer that measured linear and rotational acceleration throughout all practices and games.

Funding

NIH K24 HD064754

National Football League Charities

W911NF-11-R-0017

R01NS089609

R01 EY028535

R01 MH099921

UL1 TR002001

TL1 TR002000

5T32EY007125-24

R21NS076176

History

Date

2019-04-08

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