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Table S1. Results were used to derive quantitative predictions of the key output model parameters of the mathematical hemodynamic model, separating between patients with SCD with and without directed therapies.

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posted on 2025-07-18, 18:21 authored by Sossena WoodSossena Wood
<p dir="ltr"><b>Table S1. Results were used to derive quantitative predictions of the key output model parameters of the mathematical hemodynamic model, separating between patients with SCD with and without directed therapies. </b></p><p dir="ltr">The results reported are based on the mean and standard deviation of the acceptable solutions in a sub-analysis comparing patients with SCD intervention (n=5) and patients without SCD intervention (n=6) to healthy controls (n=13). The differences in the parameters were statistically significant (p < 0.05, Wilcoxon rank sum test) for S<sup>(c)</sup>, S<sup>(v)</sup>, t<sup>(c)</sup>, t<sup>(v)</sup>, k, α, and w<sub>c(Autoreg)/2pi</sub>.</p><p dir="ltr">This item contains figural material referenced by the paper "Assessment of Cerebral Autoregulation and Cerebral Perfusion in Patients with Sickle Cell Disease using Frequency-Domain Near-Infrared Spectroscopy."</p>

Funding

Carnegie Mellon University’s Presidential Postdoctoral Fellowship

Neurovascular Determinants of Cognitive Function in Adults with Sickle Cell Disease

National Heart Lung and Blood Institute

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University of Pittsburgh Clinical and Translational Science Institute

National Center for Advancing Translational Sciences

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