Getting the message out.

2008-07-11T00:00:00Z (GMT) by C. Joel McManus Brenton R. Graveley

In a recent issue of Molecular Cell, Schwer (2008) demonstrates that, during the latest stage of the splicing reaction, the RNA-dependent helicase Prp22 is deposited upon the downstream exon, where it subsequently strips the spliced messenger RNA from the spliceosome.