Striatal interneurons: causes of or cures for movement disorders?
Imagine one day you notice a tremor and can't walk easily anymore. Your doctor tells you that you have Parkinson's disease and gives you levodopa, a 60-year-old treatment that temporarily relieves your symptoms. But over time, the medication makes you impulsive, and after a few years, your symptoms return. The doctor tells you that you have developed resistance to your medicine and that nothing else is likely to work—your condition continues to degenerate. Sadly, this is the reality for millions of Americans suffering from Parkinson's disease.