Carnegie Mellon University
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CancerPosterFinal - Nada Alnajar.pdf (779.57 kB)

Evaluating The Effects of The Plant Cardinal Basil on Proliferation and Migration of Breast Tumor Cells

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posted on 2024-06-28, 19:56 authored by Nada Al-Najar

Cardinal basil, botanically classified as Ocimum basilicum, is a plant that is considered local to Qatar. In addition to being rich in vitamins, cardinal basil is also rich in phenolic acid and flavonoids, elucidating anti-cancer & anti-inflammatory properties [1]. The aim of this study is to look at how cardinal basil affects the proliferation of breast tumor cells. Two extraction methods, infusion via sonication and essential oil extraction via hydro distillation, were employed to produce extracts for evaluation. To identify compounds within the extracts, High Performance Liquid Chromatography (HPLC) was utilized to identify compounds within the extracts. Our results imply that both distillate and infusion extracts at 25% concentration had significant effects on cell proliferation, with 50% concentration showing the greatest efficacy in reducing cell viability. Interestingly, HPLC revealed the presence of Rosmarinic and Caffeic acids as the main components in infusion, highlighting their potential role in the tested crude extracts. 

History

Date

2024-04-30

Academic Program

  • Biological Sciences

Advisor(s)

Nesrine Affara

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